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SMILES: CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCC3)cccc12

InChI Key: InChIKey=QECQIZIVMWVPGS-VWLOTQADSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489721   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM489721
PNG
((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...)
Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCC3)cccc12 |r|
Show InChI InChI=1S/C29H35N3O4S/c1-29(2,3)32-37(35,36)26-18-10-15-22-23(26)16-9-17-24(22)30-28(34)25(19-20-11-5-4-6-12-20)31-27(33)21-13-7-8-14-21/h4-6,9-12,15-18,21,25,32H,7-8,13-14,19H2,1-3H3,(H,30,34)(H,31,33)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 370n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM489721
PNG
((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...)
Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCC3)cccc12 |r|
Show InChI InChI=1S/C29H35N3O4S/c1-29(2,3)32-37(35,36)26-18-10-15-22-23(26)16-9-17-24(22)30-28(34)25(19-20-11-5-4-6-12-20)31-27(33)21-13-7-8-14-21/h4-6,9-12,15-18,21,25,32H,7-8,13-14,19H2,1-3H3,(H,30,34)(H,31,33)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 366n/an/an/an/an/an/a



Mitobridge, Inc.

US Patent


Assay Description
The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...


US Patent US10968172 (2021)

More data for this
Ligand-Target Pair