BDBM49214 2-Hydroxy-N-p-tolylbenzamide (10)::2-hydroxy-N-(4-methylphenyl)benzamide::2-hydroxy-N-(p-tolyl)benzamide::MLS000053968::N-(4-methylphenyl)-2-oxidanyl-benzamide::SMR000061984::cid_478805

SMILES: Cc1ccc(NC(=O)c2ccccc2O)cc1

InChI Key: InChIKey=QMLRNTPTRWMCOP-UHFFFAOYSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 49214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM49214 (2-Hydroxy-N-p-tolylbenzamide (10) | 2-hydroxy-N-(4...) Show SMILES Cc1ccc(NC(=O)c2ccccc2O)cc1 Show InChI InChI=1S/C14H13NO2/c1-10-6-8-11(9-7-10)15-14(17)12-4-2-3-5-13(12)16/h2-9,16H,1H3,(H,15,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (EGFR) (Homo sapiens (Human))	BDBM49214 (2-Hydroxy-N-p-tolylbenzamide (10) | 2-hydroxy-N-(4...) Show SMILES Cc1ccc(NC(=O)c2ccccc2O)cc1 Show InChI InChI=1S/C14H13NO2/c1-10-6-8-11(9-7-10)15-14(17)12-4-2-3-5-13(12)16/h2-9,16H,1H3,(H,15,17)	PDB GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	7.4	25
Nanjing University					Assay Description Compounds 1-32 were dissolved in 100% DMSO and diluted to the appropriate concentrations with 25 mM HEPES at pH 7.4. In each well, 10 μL of comp...				J Enzyme Inhib Med Chem 26: 37-45 (2011) Article DOI: 10.3109/14756361003671060 BindingDB Entry DOI: 10.7270/Q2XW4HPN
					More data for this Ligand-Target Pair
tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens] (Homo sapiens (Human))	BDBM49214 (2-Hydroxy-N-p-tolylbenzamide (10) | 2-hydroxy-N-(4...) Show SMILES Cc1ccc(NC(=O)c2ccccc2O)cc1 Show InChI InChI=1S/C14H13NO2/c1-10-6-8-11(9-7-10)15-14(17)12-4-2-3-5-13(12)16/h2-9,16H,1H3,(H,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	9.45E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2P55M4P
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM49214 (2-Hydroxy-N-p-tolylbenzamide (10) | 2-hydroxy-N-(4...) Show SMILES Cc1ccc(NC(=O)c2ccccc2O)cc1 Show InChI InChI=1S/C14H13NO2/c1-10-6-8-11(9-7-10)15-14(17)12-4-2-3-5-13(12)16/h2-9,16H,1H3,(H,15,17)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.55E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK
					More data for this Ligand-Target Pair