Found 14 hits for monomerid = 50000102 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Gamma-aminobutyric acid type B receptor subunit 1
(Rattus norvegicus (Rat)) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
J Neurochem 32: 713-8 (1979)
Article DOI: 10.1111/j.1471-4159.1979.tb04553.x BindingDB Entry DOI: 10.7270/Q29W0D0B |
More data for this Ligand-Target Pair | |
Proton-coupled amino acid transporter 1
(Homo sapiens (Human)) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 2.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting |
Bioorg Med Chem 19: 6409-18 (2011)
Checked by Author Article DOI: 10.1016/j.bmc.2011.08.058 BindingDB Entry DOI: 10.7270/Q2NZ882D |
More data for this Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1
(RAT) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| PubMed
| n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord ... |
J Med Chem 35: 233-41 (1992)
BindingDB Entry DOI: 10.7270/Q26W9911 |
More data for this Ligand-Target Pair | |
GABA transporter
(Mus musculus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig-Maximilians-University Munich
Curated by ChEMBL
| Assay Description Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in human HEK cells |
Eur J Med Chem 46: 1483-98 (2011)
Article DOI: 10.1016/j.ejmech.2011.01.042 BindingDB Entry DOI: 10.7270/Q2F76CWJ |
More data for this Ligand-Target Pair | |
GABA transporter
(Mus musculus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 2.57E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig-Maximilians-University Munich
Curated by ChEMBL
| Assay Description Inhibition of mouse GAT1-mediated [3H]GABA uptake expressed in human HEK cells |
Eur J Med Chem 46: 1483-98 (2011)
Article DOI: 10.1016/j.ejmech.2011.01.042 BindingDB Entry DOI: 10.7270/Q2F76CWJ |
More data for this Ligand-Target Pair | |
GABA transporter
(Mus musculus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
GABA transporter 3
(Homo sapiens (Human)) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 4.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis |
ACS Med Chem Lett 5: 889-93 (2014)
Article DOI: 10.1021/ml500134k BindingDB Entry DOI: 10.7270/Q2WH2RS1 |
More data for this Ligand-Target Pair | |
GABA transporter 2
(Homo sapiens (Human)) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis |
ACS Med Chem Lett 5: 889-93 (2014)
Article DOI: 10.1021/ml500134k BindingDB Entry DOI: 10.7270/Q2WH2RS1 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent GABA transporter 1
(Rattus norvegicus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| | n/a | n/a | 2.95E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
GABA transporter
(Mus musculus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| | n/a | n/a | 1.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
GABA transporter
(Mus musculus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| | n/a | n/a | 6.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
GABA transporter 2
(Homo sapiens (Human)) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 2.09E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis |
Bioorg Med Chem 21: 4938-50 (2013)
Article DOI: 10.1016/j.bmc.2013.06.063 BindingDB Entry DOI: 10.7270/Q2NZ891C |
More data for this Ligand-Target Pair | |
GABA transporter 3
(Homo sapiens (Human)) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 4.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis |
Bioorg Med Chem 21: 4938-50 (2013)
Article DOI: 10.1016/j.bmc.2013.06.063 BindingDB Entry DOI: 10.7270/Q2NZ891C |
More data for this Ligand-Target Pair | |
GABA transporter
(Mus musculus) | BDBM50000102
(3-aminopropanoic acidbeta-alanine | Alanine-beta |...)Show InChI InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 3.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig-Maximilians-University Munich
Curated by ChEMBL
| Assay Description Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cells |
Eur J Med Chem 46: 1483-98 (2011)
Article DOI: 10.1016/j.ejmech.2011.01.042 BindingDB Entry DOI: 10.7270/Q2F76CWJ |
More data for this Ligand-Target Pair | |