BDBM50001263 5,7-Dichloro-4-hydroxy-3-(4-hydroxy-phenyl)-1H-quinolin-2-one::CHEMBL114610

SMILES: Oc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O

InChI Key: InChIKey=CBQHDIDBKFOQCM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001263 (5,7-Dichloro-4-hydroxy-3-(4-hydroxy-phenyl)-1H-qui...) Show SMILES Oc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O Show InChI InChI=1S/C15H9Cl2NO3/c16-8-5-10(17)13-11(6-8)18-15(21)12(14(13)20)7-1-3-9(19)4-2-7/h1-6,19H,(H2,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
					More data for this Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50001263 (5,7-Dichloro-4-hydroxy-3-(4-hydroxy-phenyl)-1H-qui...) Show SMILES Oc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O Show InChI InChI=1S/C15H9Cl2NO3/c16-8-5-10(17)13-11(6-8)18-15(21)12(14(13)20)7-1-3-9(19)4-2-7/h1-6,19H,(H2,18,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for in vitro inhibition of spinal cord at NMDA receptor.				J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT
					More data for this Ligand-Target Pair