BDBM50001264 5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one::CHEMBL419940

SMILES: Cc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O

InChI Key: InChIKey=DZTJUPACBLYKGU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001264 (5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...) Show SMILES Cc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O Show InChI InChI=1S/C16H11Cl2NO2/c1-8-2-4-9(5-3-8)13-15(20)14-11(18)6-10(17)7-12(14)19-16(13)21/h2-7H,1H3,(H2,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.				J Med Chem 35: 3423-5 (1992) BindingDB Entry DOI: 10.7270/Q2RR1X68
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001264 (5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...) Show SMILES Cc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O Show InChI InChI=1S/C16H11Cl2NO2/c1-8-2-4-9(5-3-8)13-15(20)14-11(18)6-10(17)7-12(14)19-16(13)21/h2-7H,1H3,(H2,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.				J Med Chem 35: 3423-5 (1992) BindingDB Entry DOI: 10.7270/Q2RR1X68
					More data for this Ligand-Target Pair