BDBM50001270 2-(2-(quinolin-2-yl)vinyl)phenol::2-(2-Quinolin-2-yl-vinyl)-phenol::CHEMBL127545

SMILES: Oc1ccccc1\C=C\c1ccc2ccccc2n1

InChI Key: InChIKey=NXNDEWNGCMCWMA-ZRDIBKRKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50001270 (2-(2-(quinolin-2-yl)vinyl)phenol | 2-(2-Quinolin-2...) Show SMILES Oc1ccccc1\C=C\c1ccc2ccccc2n1 Show InChI InChI=1S/C17H13NO/c19-17-8-4-2-6-14(17)10-12-15-11-9-13-5-1-3-7-16(13)18-15/h1-12,19H/b12-10+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3832-44 (1992) BindingDB Entry DOI: 10.7270/Q2TQ625N
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50001270 (2-(2-(quinolin-2-yl)vinyl)phenol | 2-(2-Quinolin-2...) Show SMILES Oc1ccccc1\C=C\c1ccc2ccccc2n1 Show InChI InChI=1S/C17H13NO/c19-17-8-4-2-6-14(17)10-12-15-11-9-13-5-1-3-7-16(13)18-15/h1-12,19H/b12-10+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mount Sinai School of Medicine Curated by ChEMBL					Assay Description Inhibition of Neprilysin (unknown origin)				J Med Chem 51: 3378-87 (2008) Article DOI: 10.1021/jm7015478 BindingDB Entry DOI: 10.7270/Q2319VN5
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 2 (ECE-2) (Homo sapiens (Human))	BDBM50001270 (2-(2-(quinolin-2-yl)vinyl)phenol | 2-(2-Quinolin-2...) Show SMILES Oc1ccccc1\C=C\c1ccc2ccccc2n1 Show InChI InChI=1S/C17H13NO/c19-17-8-4-2-6-14(17)10-12-15-11-9-13-5-1-3-7-16(13)18-15/h1-12,19H/b12-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mount Sinai School of Medicine Curated by ChEMBL					Assay Description Reduction of recombinant ECE2 (unknown origin) activity measured by McaBk2 fluorescent substrate hydrolysis				J Med Chem 51: 3378-87 (2008) Article DOI: 10.1021/jm7015478 BindingDB Entry DOI: 10.7270/Q2319VN5
					More data for this Ligand-Target Pair