BDBM50002466 AZTMPNPP3'-azido-3'-deoxythymidine 5'-[alpha,beta-imido]triphosphate
SMILES: Cc1cn([C@H]2C[C@@H](N=[N+]=[N-])[C@@H](OP([O-])(=O)NP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O
InChI Key: InChIKey=ALOAKUKTJBJNDK-ATRFCDNQSA-J
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50002466 (AZTMPNPP3'-azido-3'-deoxythymidine 5'-[alpha,beta-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT). | J Med Chem 35: 1938-41 (1992) BindingDB Entry DOI: 10.7270/Q25B0336 | |||||||||||
More data for this Ligand-Target Pair |