BDBM50002756 5-(2-Benzenesulfonylamino-ethylsulfanyl)-5H-dibenzo[a,d]cycloheptene-3-carboxylic acid::CHEMBL415239

SMILES: OC(=O)c1ccc2C=Cc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1

InChI Key: InChIKey=DUJNXVXZBCKKHP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50002756 (5-(2-Benzenesulfonylamino-ethylsulfanyl)-5H-dibenz...) Show SMILES OC(=O)c1ccc2C=Cc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1 |c:7| Show InChI InChI=1S/C24H21NO4S2/c26-24(27)19-13-12-18-11-10-17-6-4-5-9-21(17)23(22(18)16-19)30-15-14-25-31(28,29)20-7-2-1-3-8-20/h1-13,16,23,25H,14-15H2,(H,26,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligand				J Med Chem 35: 3394-402 (1992) BindingDB Entry DOI: 10.7270/Q2NS0SV5
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50002756 (5-(2-Benzenesulfonylamino-ethylsulfanyl)-5H-dibenz...) Show SMILES OC(=O)c1ccc2C=Cc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1 |c:7| Show InChI InChI=1S/C24H21NO4S2/c26-24(27)19-13-12-18-11-10-17-6-4-5-9-21(17)23(22(18)16-19)30-15-14-25-31(28,29)20-7-2-1-3-8-20/h1-13,16,23,25H,14-15H2,(H,26,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Binding affinity at TXA2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets				J Med Chem 35: 3394-402 (1992) BindingDB Entry DOI: 10.7270/Q2NS0SV5
					More data for this Ligand-Target Pair