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BDBM50003382 2-Ethyl-6-(2-fluoro-ethoxy)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-quinoline::CHEMBL128389

SMILES: CCc1cc(OCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2cc(OCCF)ccc2n1

InChI Key: InChIKey=MKPLRVPHRDVIRY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003382   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(Cavia porcellus)		BDBM50003382
PNG
(2-Ethyl-6-(2-fluoro-ethoxy)-4-[2'-(1H-tetrazol-5-y...)
Show SMILES CCc1cc(OCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2cc(OCCF)ccc2n1
Show InChI InChI=1S/C27H24FN5O2/c1-2-20-15-26(24-16-21(34-14-13-28)11-12-25(24)29-20)35-17-18-7-9-19(10-8-18)22-5-3-4-6-23(22)27-30-32-33-31-27/h3-12,15-16H,2,13-14,17H2,1H3,(H,30,31,32,33)
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PC sid
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PubMed
n/an/a 70n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparation

J Med Chem 35: 4027-38 (1992)


BindingDB Entry DOI: 10.7270/Q2G44P8Q
More data for this
Ligand-Target Pair