BDBM50004524 CHEMBL3233667

SMILES: Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1

InChI Key: InChIKey=IVCAEPYRFIZWLG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50004524 (CHEMBL3233667) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1 Show InChI InChI=1S/C27H36N4O3.ClH/c1-27(22-12-6-4-7-13-22)25(32)28(2)26(33)31(27)17-11-5-10-16-29-18-20-30(21-19-29)23-14-8-9-15-24(23)34-3;/h4,6-9,12-15H,5,10-11,16-21H2,1-3H3;1H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation countin...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50004524 (CHEMBL3233667) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1 Show InChI InChI=1S/C27H36N4O3.ClH/c1-27(22-12-6-4-7-13-22)25(32)28(2)26(33)31(27)17-11-5-10-16-29-18-20-30(21-19-29)23-14-8-9-15-24(23)34-3;/h4,6-9,12-15H,5,10-11,16-21H2,1-3H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human recombinant 5-HT7 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting anal...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50004524 (CHEMBL3233667) Show SMILES Cl.COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1 Show InChI InChI=1S/C27H36N4O3.ClH/c1-27(22-12-6-4-7-13-22)25(32)28(2)26(33)31(27)17-11-5-10-16-29-18-20-30(21-19-29)23-14-8-9-15-24(23)34-3;/h4,6-9,12-15H,5,10-11,16-21H2,1-3H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analy...				Eur J Med Chem 78: 324-39 (2014) Article DOI: 10.1016/j.ejmech.2014.01.065 BindingDB Entry DOI: 10.7270/Q2J104Q0
					More data for this Ligand-Target Pair