BDBM50004821 2,3,4,5-Tetrahydro-1H-benzo[d]azepine-7,8-diol::CHEMBL57873::SK&F-39315A::SK-39315A

SMILES: Oc1cc2CCNCCc2cc1O

InChI Key: InChIKey=LPJMTSQTVDKBCO-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM50004821 (2,3,4,5-Tetrahydro-1H-benzo[d]azepine-7,8-diol | C...) Show SMILES Oc1cc2CCNCCc2cc1O Show InChI InChI=1S/C10H13NO2/c12-9-5-7-1-3-11-4-2-8(7)6-10(9)13/h5-6,11-13H,1-4H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for binding affinity against dDopamine receptor D1 using [3H]fenoldopam as a radioligand				J Med Chem 29: 1904-12 (1986) BindingDB Entry DOI: 10.7270/Q2TQ623R
					More data for this Ligand-Target Pair
Adenylate cyclase (Homo sapiens (Human))	BDBM50004821 (2,3,4,5-Tetrahydro-1H-benzo[d]azepine-7,8-diol | C...) Show SMILES Oc1cc2CCNCCc2cc1O Show InChI InChI=1S/C10H13NO2/c12-9-5-7-1-3-11-4-2-8(7)6-10(9)13/h5-6,11-13H,1-4H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description Compound was tested for the adenylate cyclase stimulation				J Med Chem 35: 502-7 (1992) BindingDB Entry DOI: 10.7270/Q2TH8N95
					More data for this Ligand-Target Pair