BDBM50006943 CHEMBL3237256

SMILES: COC(=O)c1ccc(cc1)C1N(CCc2c[nH]c3ccccc23)C(=O)C(O)=C1C(=O)c1cccnc1

InChI Key: InChIKey=BXWVWUDCGOGEIF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50006943 (CHEMBL3237256) Show SMILES COC(=O)c1ccc(cc1)C1N(CCc2c[nH]c3ccccc23)C(=O)C(O)=C1C(=O)c1cccnc1 |c:29| Show InChI InChI=1S/C28H23N3O5/c1-36-28(35)18-10-8-17(9-11-18)24-23(25(32)20-5-4-13-29-15-20)26(33)27(34)31(24)14-12-19-16-30-22-7-3-2-6-21(19)22/h2-11,13,15-16,24,30,33H,12,14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...				J Med Chem 57: 2334-56 (2014) Article DOI: 10.1021/jm401695d BindingDB Entry DOI: 10.7270/Q2SB4786
					More data for this Ligand-Target Pair