BDBM50007009 CHEMBL3237285

SMILES: COC(=O)c1ccc(cc1)C1N(CCc2c[nH]c3cc(Cl)ccc23)C(=O)C(O)=C1C(=O)c1cccnc1

InChI Key: InChIKey=KDQBNEAEXKTWOE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50007009 (CHEMBL3237285) Show SMILES COC(=O)c1ccc(cc1)C1N(CCc2c[nH]c3cc(Cl)ccc23)C(=O)C(O)=C1C(=O)c1cccnc1 |c:30| Show InChI InChI=1S/C28H22ClN3O5/c1-37-28(36)17-6-4-16(5-7-17)24-23(25(33)19-3-2-11-30-14-19)26(34)27(35)32(24)12-10-18-15-31-22-13-20(29)8-9-21(18)22/h2-9,11,13-15,24,31,34H,10,12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...				J Med Chem 57: 2334-56 (2014) Article DOI: 10.1021/jm401695d BindingDB Entry DOI: 10.7270/Q2SB4786
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