BDBM50007351 CHEMBL326899::N-[2-(Allyl-methyl-amino)-1-phenyl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide

SMILES: CN(CC=C)C[C@@H](N(C)C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccccc1

InChI Key: InChIKey=BJJKSMKQNRKQQY-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007351 (CHEMBL326899 | N-[2-(Allyl-methyl-amino)-1-phenyl-...) Show SMILES CN(CC=C)C[C@@H](N(C)C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccccc1 Show InChI InChI=1S/C21H24Cl2N2O/c1-4-12-24(2)15-20(17-8-6-5-7-9-17)25(3)21(26)14-16-10-11-18(22)19(23)13-16/h4-11,13,20H,1,12,14-15H2,2-3H3/t20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand				J Med Chem 34: 3149-58 (1991) BindingDB Entry DOI: 10.7270/Q2028S53
					More data for this Ligand-Target Pair