BDBM50007362 2-(3,4-Dichloro-phenyl)-N-[1-(3-hydroxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-acetamide::CHEMBL325112

SMILES: CN(C(CN1CCCC1)c1cccc(O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=NJUPSHUZOVASNE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007362 (2-(3,4-Dichloro-phenyl)-N-[1-(3-hydroxy-phenyl)-2-...) Show SMILES CN(C(CN1CCCC1)c1cccc(O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H24Cl2N2O2/c1-24(21(27)12-15-7-8-18(22)19(23)11-15)20(14-25-9-2-3-10-25)16-5-4-6-17(26)13-16/h4-8,11,13,20,26H,2-3,9-10,12,14H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand				J Med Chem 34: 3149-58 (1991) BindingDB Entry DOI: 10.7270/Q2028S53
					More data for this Ligand-Target Pair