BindingDB PrimarySearch

null

SMILES: C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=FKVJGSPOLUAUNN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007676
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor				J Med Chem 38: 1196-202 (1995) BindingDB Entry DOI: 10.7270/Q2CZ37TG
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2C receptor				J Med Chem 38: 1196-202 (1995) BindingDB Entry DOI: 10.7270/Q2CZ37TG
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cells				J Med Chem 45: 3794-804 (2002) BindingDB Entry DOI: 10.7270/Q2MW2GG0
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity against alpha-1 adrenergic receptor				J Med Chem 34: 3085-90 (1991) BindingDB Entry DOI: 10.7270/Q2FN155W
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2C NMDA receptor				J Med Chem 41: 3499-506 (1998) Article DOI: 10.1021/jm980235+ BindingDB Entry DOI: 10.7270/Q29Z95MM
University of Oregon Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Functional antagonism by electrical assays in Xenopus oocytes expressing 1A/2A NMDA receptor subtype				J Med Chem 41: 3499-506 (1998) Article DOI: 10.1021/jm980235+ BindingDB Entry DOI: 10.7270/Q29Z95MM
University of Oregon Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptor				J Med Chem 41: 3499-506 (1998) Article DOI: 10.1021/jm980235+ BindingDB Entry DOI: 10.7270/Q29Z95MM
University of Oregon Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50007676 (4-Benzyl-1-phenethyl-piperidine \| CHEMBL18222 \| CH...) Show SMILES C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibitory activity against human Chemokine receptor type 1 expressed in chinese hamster ovary cells				J Med Chem 45: 3794-804 (2002) BindingDB Entry DOI: 10.7270/Q2MW2GG0
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair