BDBM50008170 4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-butyric acid::CHEMBL24938::Lorglumide
SMILES: CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
InChI Key: InChIKey=IEKOTSCYBBDIJC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cholecystokinin receptor (RAT) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 129 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitá di Siena Curated by ChEMBL | Assay Description Binding affinity against Cholecystokinin type A receptor using [125I]-(BH)-CCK-8 as radioligand in rat pancreas. | J Med Chem 39: 860-72 (1996) Article DOI: 10.1021/jm950423p BindingDB Entry DOI: 10.7270/Q2222SVD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [125I]-CCK-OP radioligand from Cholecystokinin type A receptor in rat pancreatic acinar membrane binding assay | Bioorg Med Chem Lett 2: 1251-1256 (1992) Article DOI: 10.1016/S0960-894X(00)80224-3 BindingDB Entry DOI: 10.7270/Q24T6J92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL | Assay Description Inhibition of binding of [125I]gastrin to Cholecystokinin type B receptor from guinea pig gastric glands | J Med Chem 33: 591-5 (1990) BindingDB Entry DOI: 10.7270/Q29K4BTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Rotta Research Laboratorium Curated by ChEMBL | Assay Description Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini | J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CCKBR (RAT) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rotta Research Laboratorium Curated by ChEMBL | Assay Description Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex | J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL | Assay Description Inhibition of binding of [125I]- CCK-33 to rat pancreas | J Med Chem 33: 591-5 (1990) BindingDB Entry DOI: 10.7270/Q29K4BTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin A receptor (Cavia porcellus) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL | Assay Description Inhibition of binding of [125I]- CCK-33 to guinea pig cortex | J Med Chem 33: 591-5 (1990) BindingDB Entry DOI: 10.7270/Q29K4BTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50008170 (4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rotta Research Laboratorium Curated by ChEMBL | Assay Description Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to cholecystokinin type B receptor in rabbit gastric gland | J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11 | |||||||||||
More data for this Ligand-Target Pair |