BDBM50008997 1-Methyl-1,2-dihydro-indazol-3-one::CHEMBL412905

SMILES: Cn1[nH]c(=O)c2ccccc12

InChI Key: InChIKey=ONNIFDMRZCMQQM-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50008997 (1-Methyl-1,2-dihydro-indazol-3-one | CHEMBL412905) Show SMILES Cn1[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C8H8N2O/c1-10-7-5-3-2-4-6(7)8(11)9-10/h2-5H,1H3,(H,9,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of LTB4 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50008997 (1-Methyl-1,2-dihydro-indazol-3-one | CHEMBL412905) Show SMILES Cn1[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C8H8N2O/c1-10-7-5-3-2-4-6(7)8(11)9-10/h2-5H,1H3,(H,9,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>100	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description Ex vivo inhibition of LTB4 production was measured in dog blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Cyclooxygenase (RAT)	BDBM50008997 (1-Methyl-1,2-dihydro-indazol-3-one | CHEMBL412905) Show SMILES Cn1[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C8H8N2O/c1-10-7-5-3-2-4-6(7)8(11)9-10/h2-5H,1H3,(H,9,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of PGE-2 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair