BDBM50009096 CHEMBL3238297

SMILES: CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)NCC1CC1)S(=O)(=O)c1ccc(N)nc1

InChI Key: InChIKey=MXPQVALSAIYLCR-IBGZPJMESA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase regulatory protein (Mus musculus)	BDBM50009096 (CHEMBL3238297) Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)NCC1CC1)S(=O)(=O)c1ccc(N)nc1 |r| Show InChI InChI=1S/C22H27N5O4S2/c1-2-3-19-16-26(33(30,31)21-10-11-22(23)24-15-21)12-13-27(19)18-6-8-20(9-7-18)32(28,29)25-14-17-4-5-17/h6-11,15,17,19,25H,4-5,12-14,16H2,1H3,(H2,23,24)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	271	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...				J Med Chem 57: 3094-116 (2014) Article DOI: 10.1021/jm5000497 BindingDB Entry DOI: 10.7270/Q2V126BF
					More data for this Ligand-Target Pair
Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50009096 (CHEMBL3238297) Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)NCC1CC1)S(=O)(=O)c1ccc(N)nc1 |r| Show InChI InChI=1S/C22H27N5O4S2/c1-2-3-19-16-26(33(30,31)21-10-11-22(23)24-15-21)12-13-27(19)18-6-8-20(9-7-18)32(28,29)25-14-17-4-5-17/h6-11,15,17,19,25H,4-5,12-14,16H2,1H3,(H2,23,24)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by A...				J Med Chem 57: 3094-116 (2014) Article DOI: 10.1021/jm5000497 BindingDB Entry DOI: 10.7270/Q2V126BF
					More data for this Ligand-Target Pair