BDBM50009305 CHEMBL3233532
SMILES: OCC[C@H]1CN(CC2CCCCC2)CCN1Cc1ccc2ccccc2c1
InChI Key: InChIKey=PMDDJJIHWAUWIM-DEOSSOPVSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig)) | BDBM50009305![]() (CHEMBL3233532) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of M£nster Curated by ChEMBL | Assay Description Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysis | J Med Chem 57: 2884-94 (2014) Article DOI: 10.1021/jm401707t BindingDB Entry DOI: 10.7270/Q2T15562 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50009305![]() (CHEMBL3233532) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of M£nster Curated by ChEMBL | Assay Description Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human RPMI8226 cell membranes after 120 mins by scintillation counting analysis | J Med Chem 57: 2884-94 (2014) Article DOI: 10.1021/jm401707t BindingDB Entry DOI: 10.7270/Q2T15562 | |||||||||||
More data for this Ligand-Target Pair |