BDBM50010188 3-[4-amino(imino)methylamino-1-[4-amino(imino)methylamino-1-methylcarboxamido-(1S)-butylcarboxamido]-(1S)-butylcarboxamidomethylcarboxamido]-3-[1-carbamoyl-2-phenyl-(1S)-ethylcarbamoyl]propanoic acid::CHEMBL105092
SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key: InChIKey=QBTJJPSPQDWDKK-TUFLPTIASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50010188 (3-[4-amino(imino)methylamino-1-[4-amino(imino)meth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Inhibition of canine platelet-rich plasma agregation induced by ADP | J Med Chem 34: 3114-25 (1991) BindingDB Entry DOI: 10.7270/Q2445KF0 | |||||||||||
More data for this Ligand-Target Pair |