BDBM50010993 CHEMBL3265177
SMILES: [O-][N+](=O)c1cccc(c1)-c1nsc(=O)o1
InChI Key: InChIKey=QBAZATRGWRVUFN-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
26S proteosome (Homo sapiens (Human)) | BDBM50010993 (CHEMBL3265177) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Weill Cornell Medical College Curated by ChEMBL | Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min... | ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF | |||||||||||
More data for this Ligand-Target Pair |