BDBM50011966 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-cyclopentyloxy-phenyl)-3H-quinazolin-4-one::CHEMBL287740

SMILES: Brc1ccc2[nH]cc(CCc3nc4ccccc4c(=O)n3-c3cccc(OC4CCCC4)c3)c2c1

InChI Key: InChIKey=QJRJKKSFKCALGA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011966 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-cyclopent...) Show SMILES Brc1ccc2[nH]cc(CCc3nc4ccccc4c(=O)n3-c3cccc(OC4CCCC4)c3)c2c1 Show InChI InChI=1S/C29H26BrN3O2/c30-20-13-14-26-25(16-20)19(18-31-26)12-15-28-32-27-11-4-3-10-24(27)29(34)33(28)21-6-5-9-23(17-21)35-22-7-1-2-8-22/h3-6,9-11,13-14,16-18,22,31H,1-2,7-8,12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair