BDBM50012990 6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL544618

SMILES: CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31

InChI Key: InChIKey=YPNFSVPDCPRGIG-CQSZACIVSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012990 (6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinol...) Show SMILES CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012990 (6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinol...) Show SMILES CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012990 (6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinol...) Show SMILES CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair