BDBM50013248 CHEMBL152894::N-Benzyl-N'-[4-(4-methyl-1H-indol-3-yl)-thiazol-2-yl]-guanidine

SMILES: Cc1cccc2[nH]cc(-c3csc(N=C(N)NCc4ccccc4)n3)c12

InChI Key: InChIKey=LCVNOCZVJFVJPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 1/beta chain (Homo sapiens (Human))	BDBM50013248 (CHEMBL152894 | N-Benzyl-N'-[4-(4-methyl-1H-indol-3...) Show SMILES Cc1cccc2[nH]cc(-c3csc(N=C(N)NCc4ccccc4)n3)c12 |w:13.12| Show InChI InChI=1S/C20H19N5S/c1-13-6-5-9-16-18(13)15(11-22-16)17-12-26-20(24-17)25-19(21)23-10-14-7-3-2-4-8-14/h2-9,11-12,22H,10H2,1H3,(H3,21,23,24,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPase				J Med Chem 33: 543-52 (1990) BindingDB Entry DOI: 10.7270/Q2K35V79
					More data for this Ligand-Target Pair