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SMILES: CCOP(=O)(OCC)c1cccc(Nc2cc(ncn2)-c2ccccc2OC)c1

InChI Key: InChIKey=NXQWKBTULGIQSQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013469   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-T1/Cyclin-dependent kinase 9


(Homo sapiens (Human))		BDBM50013469
PNG
(CHEMBL3264137)
Show SMILES CCOP(=O)(OCC)c1cccc(Nc2cc(ncn2)-c2ccccc2OC)c1
Show InChI InChI=1S/C21H24N3O4P/c1-4-27-29(25,28-5-2)17-10-8-9-16(13-17)24-21-14-19(22-15-23-21)18-11-6-7-12-20(18)26-3/h6-15H,4-5H2,1-3H3,(H,22,23,24)
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Article
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n/an/a 1.04E+3n/an/an/an/an/an/a



Vichem Chemie Ltd.

Curated by ChEMBL


Assay Description
Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hr

J Med Chem 57: 3939-65 (2014)


Article DOI: 10.1021/jm401742r
BindingDB Entry DOI: 10.7270/Q28C9XRB
More data for this
Ligand-Target Pair