BDBM50014171 CHEMBL3221248

SMILES: CCOC(=O)C1=C(C)NC(=CC1c1ccccc1)c1ccccc1

InChI Key: InChIKey=PPBLJZVNNCYRIG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50014171 (CHEMBL3221248) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccccc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C21H21NO2/c1-3-24-21(23)20-15(2)22-19(17-12-8-5-9-13-17)14-18(20)16-10-6-4-7-11-16/h4-14,18,22H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair