BDBM50014333 CHEMBL3221247

SMILES: C\C(=C/c1ccccc1)C1C=C(NC(C)=C1C(=O)SC(C)(C)C)c1ccccc1

InChI Key: InChIKey=MKONNNAFOIOGDI-FBMGVBCBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium channel (RAT)	BDBM50014333 (CHEMBL3221247) Show SMILES C\C(=C/c1ccccc1)C1C=C(NC(C)=C1C(=O)SC(C)(C)C)c1ccccc1 |c:11,15| Show InChI InChI=1S/C26H29NOS/c1-18(16-20-12-8-6-9-13-20)22-17-23(21-14-10-7-11-15-21)27-19(2)24(22)25(28)29-26(3,4)5/h6-17,22,27H,1-5H3/b18-16+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50014333 (CHEMBL3221247) Show SMILES C\C(=C/c1ccccc1)C1C=C(NC(C)=C1C(=O)SC(C)(C)C)c1ccccc1 |c:11,15| Show InChI InChI=1S/C26H29NOS/c1-18(16-20-12-8-6-9-13-20)22-17-23(21-14-10-7-11-15-21)27-19(2)24(22)25(28)29-26(3,4)5/h6-17,22,27H,1-5H3/b18-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair