null

SMILES: OCCCNC(=O)c1ncncc1Nc1ccc(I)cc1F

InChI Key: InChIKey=UJOHMVNVNZUHCV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50014396 (CHEMBL3261146) Show SMILES OCCCNC(=O)c1ncncc1Nc1ccc(I)cc1F Show InChI InChI=1S/C14H14FIN4O2/c15-10-6-9(16)2-3-11(10)20-12-7-17-8-19-13(12)14(22)18-4-1-5-21/h2-3,6-8,20-21H,1,4-5H2,(H,18,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of MEK1 in human COLO205 cells				Bioorg Med Chem Lett 24: 2555-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.086 BindingDB Entry DOI: 10.7270/Q2PG1T73
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50014396 (CHEMBL3261146) Show SMILES OCCCNC(=O)c1ncncc1Nc1ccc(I)cc1F Show InChI InChI=1S/C14H14FIN4O2/c15-10-6-9(16)2-3-11(10)20-12-7-17-8-19-13(12)14(22)18-4-1-5-21/h2-3,6-8,20-21H,1,4-5H2,(H,18,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of MEK1 (unknown origin)				Bioorg Med Chem Lett 24: 2555-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.086 BindingDB Entry DOI: 10.7270/Q2PG1T73
					More data for this Ligand-Target Pair