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BDBM50015471 1-[2-(1-Carboxy-3-phenyl-propylamino)-6-(4-chloro-3-sulfamoyl-benzoylamino)-hexanoyl]-pyrrolidine-2-carboxylic acid hydrochloride::CHEMBL2448085

SMILES: Cl.NS(=O)(=O)c1cc(ccc1Cl)C(=O)NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O

InChI Key: InChIKey=VGGBMAATHKTAAR-RGRVRPFLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015471   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin-converting enzyme


(Rattus norvegicus)		BDBM50015471
PNG
(1-[2-(1-Carboxy-3-phenyl-propylamino)-6-(4-chloro-...)
Show SMILES Cl.NS(=O)(=O)c1cc(ccc1Cl)C(=O)NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C28H35ClN4O8S.ClH/c29-20-13-12-19(17-24(20)42(30,40)41)25(34)31-15-5-4-9-21(26(35)33-16-6-10-23(33)28(38)39)32-22(27(36)37)14-11-18-7-2-1-3-8-18;/h1-3,7-8,12-13,17,21-23,32H,4-6,9-11,14-16H2,(H,31,34)(H,36,37)(H,38,39)(H2,30,40,41);1H/t21-,22-,23-;/m0./s1
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 6.5n/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Angiotensin I converting enzyme (ACE)

J Med Chem 33: 1600-6 (1990)


BindingDB Entry DOI: 10.7270/Q2H41S2F
More data for this
Ligand-Target Pair