BDBM50016007 (R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL117841

SMILES: COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12

InChI Key: InChIKey=HJSGUUPPOBQDHU-OAHLLOKOSA-N

Data: 3 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016007 ((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) Show SMILES COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 Show InChI InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50016007 ((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) Show SMILES COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 Show InChI InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	551	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human Dopamine receptor D2A				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50016007 ((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) Show SMILES COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 Show InChI InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	606	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50016007 ((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) Show SMILES COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 Show InChI InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards rat Dopamine receptor D1 by [3H]-SCH-23,390 displacement.				J Med Chem 33: 600-7 (1990) BindingDB Entry DOI: 10.7270/Q2XS5TCP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50016007 ((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) Show SMILES COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 Show InChI InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards rat Dopamine receptor D2 by [3H]-spiperone displacement.				J Med Chem 33: 600-7 (1990) BindingDB Entry DOI: 10.7270/Q2XS5TCP
					More data for this Ligand-Target Pair