BDBM50016965 4,4-Dimethyl-1-{4-[4-(2-methyl-furo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-piperidine-2,6-dione; hydrochloride::CHEMBL544202
SMILES: Cc1cc2c(nccc2o1)N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1
InChI Key: InChIKey=RLIZPUXPCGFMOI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50016965 (4,4-Dimethyl-1-{4-[4-(2-methyl-furo[3,2-c]pyridin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 708 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Company Curated by ChEMBL | Assay Description Ability to bind at Dopamine receptor D2 of rat corpus striatum by displacing [3H]spiperone | J Med Chem 32: 1147-56 (1989) BindingDB Entry DOI: 10.7270/Q2HD7W8D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50016965 (4,4-Dimethyl-1-{4-[4-(2-methyl-furo[3,2-c]pyridin-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Company Curated by ChEMBL | Assay Description Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPAT | J Med Chem 32: 1147-56 (1989) BindingDB Entry DOI: 10.7270/Q2HD7W8D | |||||||||||
More data for this Ligand-Target Pair |