BDBM50017059 3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL279065

SMILES: CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1

InChI Key: InChIKey=XHBTZWGPHRHWQZ-FUHWJXTLSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50017059 (3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]d...) Show SMILES CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1 Show InChI InChI=1S/C18H24Br2N2O/c1-21-11-5-10-18(21)9-4-3-6-16(18)22(2)17(23)13-7-8-14(19)15(20)12-13/h7-8,12,16H,3-6,9-11H2,1-2H3/t16-,18+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Corporation Curated by ChEMBL					Assay Description Binding inhibition against opioid receptor kappa of guinea pig was determined using [3H]ethylketocyclazocine				J Med Chem 32: 1259-65 (1989) BindingDB Entry DOI: 10.7270/Q280536X
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50017059 (3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]d...) Show SMILES CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1 Show InChI InChI=1S/C18H24Br2N2O/c1-21-11-5-10-18(21)9-4-3-6-16(18)22(2)17(23)13-7-8-14(19)15(20)12-13/h7-8,12,16H,3-6,9-11H2,1-2H3/t16-,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Corporation Curated by ChEMBL					Assay Description Inhibitory activity against opioid receptor delta of guinea pig was determined by using [3H]DADLE radioligand				J Med Chem 32: 1259-65 (1989) BindingDB Entry DOI: 10.7270/Q280536X
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50017059 (3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]d...) Show SMILES CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1 Show InChI InChI=1S/C18H24Br2N2O/c1-21-11-5-10-18(21)9-4-3-6-16(18)22(2)17(23)13-7-8-14(19)15(20)12-13/h7-8,12,16H,3-6,9-11H2,1-2H3/t16-,18+/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Corporation Curated by ChEMBL					Assay Description Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligand				J Med Chem 32: 1259-65 (1989) BindingDB Entry DOI: 10.7270/Q280536X
					More data for this Ligand-Target Pair