BDBM50017616 7-Fluoro-2-methyl-10-morpholin-4-yl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87564

SMILES: Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCOCC2)n1

InChI Key: InChIKey=CLBYMEHHRUIOGC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50017616 (7-Fluoro-2-methyl-10-morpholin-4-yl-2,4-dihydro-2,...) Show SMILES Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCOCC2)n1 |c:14| Show InChI InChI=1S/C15H16FN5O/c1-20-9-11-14(19-20)17-12-3-2-10(16)8-13(12)18-15(11)21-4-6-22-7-5-21/h2-3,8-9H,4-7H2,1H3,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description 50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation at 3 degree C				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017616 (7-Fluoro-2-methyl-10-morpholin-4-yl-2,4-dihydro-2,...) Show SMILES Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCOCC2)n1 |c:14| Show InChI InChI=1S/C15H16FN5O/c1-20-9-11-14(19-20)17-12-3-2-10(16)8-13(12)18-15(11)21-4-6-22-7-5-21/h2-3,8-9H,4-7H2,1H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Centre Limited Curated by ChEMBL					Assay Description Inhibition of [3H]spiperone binding to Dopamine receptor D2 from striatum of the rat brain				J Med Chem 32: 2573-82 (1989) BindingDB Entry DOI: 10.7270/Q22F7P2J
					More data for this Ligand-Target Pair