BDBM50017887 CHEMBL3289009

SMILES: FC(F)(F)c1ccnc(Nc2ccc3NC(=O)CSc3c2)c1

InChI Key: InChIKey=URYSLFPRZAGVOS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50017887 (CHEMBL3289009) Show SMILES FC(F)(F)c1ccnc(Nc2ccc3NC(=O)CSc3c2)c1 Show InChI InChI=1S/C14H10F3N3OS/c15-14(16,17)8-3-4-18-12(5-8)19-9-1-2-10-11(6-9)22-7-13(21)20-10/h1-6H,7H2,(H,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair