BDBM50018792 (L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxylic acid::(S)-1-(3-mercaptopropanoyl)pyrrolidine-2-carboxylic acid::1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxylic acid::1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxylic acid(Captopril analogue)::CHEMBL10962

SMILES: OC(=O)[C@@H]1CCCN1C(=O)CCS

InChI Key: InChIKey=HYIXVZHJZDSDBA-LURJTMIESA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50018792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50018792 ((L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxy...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)CCS |r| Show InChI InChI=1S/C8H13NO3S/c10-7(3-5-13)9-4-1-2-6(9)8(11)12/h6,13H,1-5H2,(H,11,12)/t6-/m0/s1	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.				J Med Chem 30: 992-8 (1987) BindingDB Entry DOI: 10.7270/Q29C6Z02
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50018792 ((L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxy...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)CCS |r| Show InChI InChI=1S/C8H13NO3S/c10-7(3-5-13)9-4-1-2-6(9)8(11)12/h6,13H,1-5H2,(H,11,12)/t6-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme in rabbit lung, using hippuryl-histidyl-leucine as substrate				J Med Chem 25: 250-8 (1982) BindingDB Entry DOI: 10.7270/Q28053SJ
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50018792 ((L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxy...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)CCS |r| Show InChI InChI=1S/C8H13NO3S/c10-7(3-5-13)9-4-1-2-6(9)8(11)12/h6,13H,1-5H2,(H,11,12)/t6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin converting enzyme (ACE)				J Med Chem 36: 2390-403 (1993) BindingDB Entry DOI: 10.7270/Q2Z320V9
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50018792 ((L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxy...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)CCS |r| Show InChI InChI=1S/C8H13NO3S/c10-7(3-5-13)9-4-1-2-6(9)8(11)12/h6,13H,1-5H2,(H,11,12)/t6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin converting enzyme (ACE)				J Med Chem 36: 2390-403 (1993) BindingDB Entry DOI: 10.7270/Q2Z320V9
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50018792 ((L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxy...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)CCS |r| Show InChI InChI=1S/C8H13NO3S/c10-7(3-5-13)9-4-1-2-6(9)8(11)12/h6,13H,1-5H2,(H,11,12)/t6-/m0/s1	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive rats				J Med Chem 28: 1067-71 (1985) BindingDB Entry DOI: 10.7270/Q2CJ8FPX
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50018792 ((L)-1-(3-Mercapto-propionyl)-pyrrolidine-2-carboxy...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)CCS |r| Show InChI InChI=1S/C8H13NO3S/c10-7(3-5-13)9-4-1-2-6(9)8(11)12/h6,13H,1-5H2,(H,11,12)/t6-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description In vitro inhibition of Angiotensin I converting enzyme with relative to captopril(=1)				J Med Chem 31: 875-85 (1988) BindingDB Entry DOI: 10.7270/Q2GT5NRV
					More data for this Ligand-Target Pair