BDBM50018922 CHEMBL3287109

SMILES: OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CCc3c(Cl)c(Cl)ccc-23)s1

InChI Key: InChIKey=XCEJCUSUGFIQIE-OYKKKHCWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018922 (CHEMBL3287109) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CCc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C20H14Cl2N4O4S/c21-13-7-5-12-11(17(13)22)6-8-16-18(12)23-20(31-16)25-24-14(19(27)28)9-10-3-1-2-4-15(10)26(29)30/h1-5,7H,6,8-9H2,(H,23,25)(H,27,28)/b24-14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair