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SMILES: FC(F)(F)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=PBYGTZDDQVQREH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019077 (CHEMBL3288333) Show SMILES FC(F)(F)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H17F6NO/c21-19(22,23)15-5-3-4-14(12-15)18(28)27-10-8-13(9-11-27)16-6-1-2-7-17(16)20(24,25)26/h1-7,12-13H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysis				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Homo sapiens (Human))	BDBM50019077 (CHEMBL3288333) Show SMILES FC(F)(F)c1cccc(c1)C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H17F6NO/c21-19(22,23)15-5-3-4-14(12-15)18(28)27-10-8-13(9-11-27)16-6-1-2-7-17(16)20(24,25)26/h1-7,12-13H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assay				Bioorg Med Chem Lett 24: 2885-91 (2014) Article DOI: 10.1016/j.bmcl.2014.04.089 BindingDB Entry DOI: 10.7270/Q2154JMV
					More data for this Ligand-Target Pair