BDBM50019547 CHEMBL77048::N-[3-(4-Acetyl-3-fluoro-phenoxymethyl)-phenyl]-succinamic acid methyl ester

SMILES: COC(=O)CCC(=O)Nc1cccc(COc2ccc(C(C)=O)c(F)c2)c1

InChI Key: InChIKey=GQJCXKMJIUKWSM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50019547 (CHEMBL77048 | N-[3-(4-Acetyl-3-fluoro-phenoxymethy...) Show SMILES COC(=O)CCC(=O)Nc1cccc(COc2ccc(C(C)=O)c(F)c2)c1 Show InChI InChI=1S/C20H20FNO5/c1-13(23)17-7-6-16(11-18(17)21)27-12-14-4-3-5-15(10-14)22-19(24)8-9-20(25)26-2/h3-7,10-11H,8-9,12H2,1-2H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibition of 5-HETE production in isolated rat polymorphonuclear leukocytes (PMNs)				J Med Chem 29: 2329-34 (1986) BindingDB Entry DOI: 10.7270/Q2TH8KNT
					More data for this Ligand-Target Pair