BDBM50022114 CHEMBL3298225

SMILES: COc1cccc2ncnc(NCC(C)(C)c3ccccc3)c12

InChI Key: InChIKey=LDYUFSLJMKARCD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50022114 (CHEMBL3298225) Show SMILES COc1cccc2ncnc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C19H21N3O/c1-19(2,14-8-5-4-6-9-14)12-20-18-17-15(21-13-22-18)10-7-11-16(17)23-3/h4-11,13H,12H2,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair