BDBM50022556 2-Dichloromethyl-4-hydroxy-8-trifluoromethyl-quinoline-3-carboxylic acid thiazol-2-ylamide::CHEMBL285278

SMILES: Oc1c(C(=O)Nc2nccs2)c(nc2c(cccc12)C(F)(F)F)C(Cl)Cl

InChI Key: InChIKey=GLLLSFSHYFLEMU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Bos taurus)	BDBM50022556 (2-Dichloromethyl-4-hydroxy-8-trifluoromethyl-quino...) Show SMILES Oc1c(C(=O)Nc2nccs2)c(nc2c(cccc12)C(F)(F)F)C(Cl)Cl Show InChI InChI=1S/C15H8Cl2F3N3O2S/c16-12(17)10-8(13(25)23-14-21-4-5-26-14)11(24)6-2-1-3-7(9(6)22-10)15(18,19)20/h1-5,12H,(H,22,24)(H,21,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Roussel Uclaf Curated by ChEMBL					Assay Description Inhibition of bovine Prostaglandin G/H synthase after oral administration				J Med Chem 31: 1453-62 (1988) BindingDB Entry DOI: 10.7270/Q2JM2B7T
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50022556 (2-Dichloromethyl-4-hydroxy-8-trifluoromethyl-quino...) Show SMILES Oc1c(C(=O)Nc2nccs2)c(nc2c(cccc12)C(F)(F)F)C(Cl)Cl Show InChI InChI=1S/C15H8Cl2F3N3O2S/c16-12(17)10-8(13(25)23-14-21-4-5-26-14)11(24)6-2-1-3-7(9(6)22-10)15(18,19)20/h1-5,12H,(H,22,24)(H,21,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Roussel Uclaf Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administration				J Med Chem 31: 1453-62 (1988) BindingDB Entry DOI: 10.7270/Q2JM2B7T
					More data for this Ligand-Target Pair