null

SMILES: Oc1c(nc([nH]c1=O)-c1ccc(F)cc1)C(=O)NCc1ccc(F)c(Cl)c1

InChI Key: InChIKey=YJCIOHLDVOHJLV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50023434 (CHEMBL3334645) Show SMILES Oc1c(nc([nH]c1=O)-c1ccc(F)cc1)C(=O)NCc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H12ClF2N3O3/c19-12-7-9(1-6-13(12)21)8-22-17(26)14-15(25)18(27)24-16(23-14)10-2-4-11(20)5-3-10/h1-7,25H,8H2,(H,22,26)(H,23,24,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type integrase strand transfer activity by gel-based assay				Bioorg Med Chem 22: 5446-53 (2014) Article DOI: 10.1016/j.bmc.2014.07.036 BindingDB Entry DOI: 10.7270/Q2WM1G02
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50023434 (CHEMBL3334645) Show SMILES Oc1c(nc([nH]c1=O)-c1ccc(F)cc1)C(=O)NCc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C18H12ClF2N3O3/c19-12-7-9(1-6-13(12)21)8-22-17(26)14-15(25)18(27)24-16(23-14)10-2-4-11(20)5-3-10/h1-7,25H,8H2,(H,22,26)(H,23,24,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type integrase 3'-processing activity by gel-based assays				Bioorg Med Chem 22: 5446-53 (2014) Article DOI: 10.1016/j.bmc.2014.07.036 BindingDB Entry DOI: 10.7270/Q2WM1G02
					More data for this Ligand-Target Pair