BDBM50023440 CHEMBL3334639

SMILES: Oc1c(nc([nH]c1=O)-c1ccc(F)cc1)C(=O)NCCc1ccc(F)cc1

InChI Key: InChIKey=BTLZWDLPNDTPJQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023440   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50023440 (CHEMBL3334639) Show SMILES Oc1c(nc([nH]c1=O)-c1ccc(F)cc1)C(=O)NCCc1ccc(F)cc1 Show InChI InChI=1S/C19H15F2N3O3/c20-13-5-1-11(2-6-13)9-10-22-18(26)15-16(25)19(27)24-17(23-15)12-3-7-14(21)8-4-12/h1-8,25H,9-10H2,(H,22,26)(H,23,24,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type integrase strand transfer activity by gel-based assay				Bioorg Med Chem 22: 5446-53 (2014) Article DOI: 10.1016/j.bmc.2014.07.036 BindingDB Entry DOI: 10.7270/Q2WM1G02
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50023440 (CHEMBL3334639) Show SMILES Oc1c(nc([nH]c1=O)-c1ccc(F)cc1)C(=O)NCCc1ccc(F)cc1 Show InChI InChI=1S/C19H15F2N3O3/c20-13-5-1-11(2-6-13)9-10-22-18(26)15-16(25)19(27)24-17(23-15)12-3-7-14(21)8-4-12/h1-8,25H,9-10H2,(H,22,26)(H,23,24,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type integrase 3'-processing activity by gel-based assays				Bioorg Med Chem 22: 5446-53 (2014) Article DOI: 10.1016/j.bmc.2014.07.036 BindingDB Entry DOI: 10.7270/Q2WM1G02
					More data for this Ligand-Target Pair