BDBM50023497 9-Chloro-2-(tetrahydro-furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine::CHEMBL7511

SMILES: Nc1nc2ccc(Cl)cc2c2nc(nn12)C1CCCO1

InChI Key: InChIKey=BVFLWFQFKAPQFY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50023497 (9-Chloro-2-(tetrahydro-furan-2-yl)-[1,2,4]triazolo...) Show SMILES Nc1nc2ccc(Cl)cc2c2nc(nn12)C1CCCO1 Show InChI InChI=1S/C13H12ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h3-4,6,10H,1-2,5H2,(H2,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatum				J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50023497 (9-Chloro-2-(tetrahydro-furan-2-yl)-[1,2,4]triazolo...) Show SMILES Nc1nc2ccc(Cl)cc2c2nc(nn12)C1CCCO1 Show InChI InChI=1S/C13H12ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h3-4,6,10H,1-2,5H2,(H2,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	827	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes.				J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W
					More data for this Ligand-Target Pair