BDBM50026245 CHEMBL3359029
SMILES: [H][C@@]12C[C@@H](C[C@]1([H])CN(C2)C(=O)N[C@@H](C(O)=O)c1ccccc1)c1ccccc1C(F)(F)F
InChI Key: InChIKey=IMSUFFXERQWSIB-PDOICOKGSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinol-binding protein 4 (Homo sapiens (Human)) | BDBM50026245![]() (CHEMBL3359029) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research Curated by ChEMBL | Assay Description Antagonist activity at maltose binding protein-tagged RBP4 (unknown origin) expressed in Escherichia coli assessed as inhibition of retinol-induced p... | J Med Chem 57: 7731-57 (2014) Article DOI: 10.1021/jm5010013 BindingDB Entry DOI: 10.7270/Q2FB54JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinol-binding protein 4 (Homo sapiens (Human)) | BDBM50026245![]() (CHEMBL3359029) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research Curated by ChEMBL | Assay Description Displacement of [3H]retinol from biotinylated human RBP4 by scintillation proximity assay | J Med Chem 57: 7731-57 (2014) Article DOI: 10.1021/jm5010013 BindingDB Entry DOI: 10.7270/Q2FB54JT | |||||||||||
More data for this Ligand-Target Pair |