BDBM50026421 CHEMBL3331280

SMILES: Cc1nc2ccc(Cl)cc2c(=O)n1CC(=O)Nc1cc(ccc1Cl)C(C)(F)F

InChI Key: InChIKey=RVHCAQPZPCJBPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (InhA) (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50026421 (CHEMBL3331280) Show SMILES Cc1nc2ccc(Cl)cc2c(=O)n1CC(=O)Nc1cc(ccc1Cl)C(C)(F)F Show InChI InChI=1S/C19H15Cl2F2N3O2/c1-10-24-15-6-4-12(20)8-13(15)18(28)26(10)9-17(27)25-16-7-11(19(2,22)23)3-5-14(16)21/h3-8H,9H2,1-2H3,(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology& Science - Pilani Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli BL21 (DE3) using 2-trans-decenoyl substrate by spectrophotome...				Eur J Med Chem 86: 613-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.028 BindingDB Entry DOI: 10.7270/Q2SJ1N7N
					More data for this Ligand-Target Pair