BDBM50027087 2-Bromo-N-[1-(2-diethylamino-ethyl)-2-(4-ethoxy-benzyl)-1H-benzoimidazol-5-yl]-acetamide::CHEMBL290440

SMILES: CCOc1ccc(Cc2nc3cc(NC(=O)CBr)ccc3n2CCN(CC)CC)cc1

InChI Key: InChIKey=BHQGYLBZJOENGC-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50027087 (2-Bromo-N-[1-(2-diethylamino-ethyl)-2-(4-ethoxy-be...) Show SMILES CCOc1ccc(Cc2nc3cc(NC(=O)CBr)ccc3n2CCN(CC)CC)cc1 Show InChI InChI=1S/C24H31BrN4O2/c1-4-28(5-2)13-14-29-22-12-9-19(26-24(30)17-25)16-21(22)27-23(29)15-18-7-10-20(11-8-18)31-6-3/h7-12,16H,4-6,13-15,17H2,1-3H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The binding affinity was evaluated against [3H]dalamid binding to rat brain membranes (Opioid receptor delta 1)				J Med Chem 27: 1570-4 (1985) BindingDB Entry DOI: 10.7270/Q2S18328
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50027087 (2-Bromo-N-[1-(2-diethylamino-ethyl)-2-(4-ethoxy-be...) Show SMILES CCOc1ccc(Cc2nc3cc(NC(=O)CBr)ccc3n2CCN(CC)CC)cc1 Show InChI InChI=1S/C24H31BrN4O2/c1-4-28(5-2)13-14-29-22-12-9-19(26-24(30)17-25)16-21(22)27-23(29)15-18-7-10-20(11-8-18)31-6-3/h7-12,16H,4-6,13-15,17H2,1-3H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The binding affinity was evaluated against [3H]dalamid binding to rat brain membranes (mu opiate receptors).				J Med Chem 27: 1570-4 (1985) BindingDB Entry DOI: 10.7270/Q2S18328
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50027087 (2-Bromo-N-[1-(2-diethylamino-ethyl)-2-(4-ethoxy-be...) Show SMILES CCOc1ccc(Cc2nc3cc(NC(=O)CBr)ccc3n2CCN(CC)CC)cc1 Show InChI InChI=1S/C24H31BrN4O2/c1-4-28(5-2)13-14-29-22-12-9-19(26-24(30)17-25)16-21(22)27-23(29)15-18-7-10-20(11-8-18)31-6-3/h7-12,16H,4-6,13-15,17H2,1-3H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The binding affinity was evaluated against [3H]dalamid binding to neuroblastoma X glioma hybrid cell NG108-15 (Opioid receptor delta 1)membranes				J Med Chem 27: 1570-4 (1985) BindingDB Entry DOI: 10.7270/Q2S18328
					More data for this Ligand-Target Pair