BDBM50027816 CHEMBL154370

SMILES: C[C@H](CNc1ccc(CC(=O)NCc2ccc(C)cc2)cc1)NC[C@H](O)c1cccc(Cl)c1

InChI Key: InChIKey=PHRSTEUVRCQEGQ-IBVKSMDESA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50027816 (CHEMBL154370) Show SMILES C[C@H](CNc1ccc(CC(=O)NCc2ccc(C)cc2)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C27H32ClN3O2/c1-19-6-8-22(9-7-19)17-31-27(33)14-21-10-12-25(13-11-21)30-16-20(2)29-18-26(32)23-4-3-5-24(28)15-23/h3-13,15,20,26,29-30,32H,14,16-18H2,1-2H3,(H,31,33)/t20-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to cause cAMP accumulation in CHO cells expressing human beta-3 AR expressed as the negative logarithm of the molar drug concentration				J Med Chem 45: 567-83 (2002) BindingDB Entry DOI: 10.7270/Q2W0976P
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50027816 (CHEMBL154370) Show SMILES C[C@H](CNc1ccc(CC(=O)NCc2ccc(C)cc2)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C27H32ClN3O2/c1-19-6-8-22(9-7-19)17-31-27(33)14-21-10-12-25(13-11-21)30-16-20(2)29-18-26(32)23-4-3-5-24(28)15-23/h3-13,15,20,26,29-30,32H,14,16-18H2,1-2H3,(H,31,33)/t20-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to cause cAMP accumulation in CHO cells expressing human beta-2 AR expressed as the negative logarithm of the molar drug concentration				J Med Chem 45: 567-83 (2002) BindingDB Entry DOI: 10.7270/Q2W0976P
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50027816 (CHEMBL154370) Show SMILES C[C@H](CNc1ccc(CC(=O)NCc2ccc(C)cc2)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C27H32ClN3O2/c1-19-6-8-22(9-7-19)17-31-27(33)14-21-10-12-25(13-11-21)30-16-20(2)29-18-26(32)23-4-3-5-24(28)15-23/h3-13,15,20,26,29-30,32H,14,16-18H2,1-2H3,(H,31,33)/t20-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to cause cAMP accumulation in CHO cells expressing human beta-1 AR expressed as the negative logarithm of the molar drug concentration				J Med Chem 45: 567-83 (2002) BindingDB Entry DOI: 10.7270/Q2W0976P
					More data for this Ligand-Target Pair