BDBM50027835 7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one::7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one( am)::7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one(desmethyldiazepam)::7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one(nordiazepam)::7-chloro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one::CHEMBL523::DESMETHYLDIAZEPAM::Gen-Xene::Nordazepam::Tranxene

SMILES: Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI Key: InChIKey=AKPLHCDWDRPJGD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Translocator protein (Homo sapiens (Human))	BDBM50027835 (7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepi...) Show SMILES Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1 |t:9| Show InChI InChI=1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.40E+9	n/a	n/a	n/a	n/a	n/a	n/a
Harvard University Curated by ChEMBL					Assay Description Binding affinity of compound towards Benzodiazepine receptor in a competition assay				J Med Chem 39: 5246-56 (1997) Article DOI: 10.1021/jm960536o BindingDB Entry DOI: 10.7270/Q2NG4RTQ
					More data for this Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50027835 (7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepi...) Show SMILES Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1 |t:9| Show InChI InChI=1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description The compound was tested for binding affinity against PBR(peripheral benzodiazepine receptor) in normal rat brain homogenate				J Med Chem 40: 1726-30 (1997) Article DOI: 10.1021/jm960592p BindingDB Entry DOI: 10.7270/Q2X929DZ
					More data for this Ligand-Target Pair