BDBM50028127 CHEMBL3353993

SMILES: C[C@H]1C[C@@H](NC=O)c2cc(ccc2N1C(C)=O)-c1ccc(CN2CCCCC2)cc1

InChI Key: InChIKey=SQABPUFSJZTJLQ-MHECFPHRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50028127 (CHEMBL3353993) Show SMILES C[C@H]1C[C@@H](NC=O)c2cc(ccc2N1C(C)=O)-c1ccc(CN2CCCCC2)cc1 |r| Show InChI InChI=1S/C25H31N3O2/c1-18-14-24(26-17-29)23-15-22(10-11-25(23)28(18)19(2)30)21-8-6-20(7-9-21)16-27-12-4-3-5-13-27/h6-11,15,17-18,24H,3-5,12-14,16H2,1-2H3,(H,26,29)/t18-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD2 (1 to 473 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50028127 (CHEMBL3353993) Show SMILES C[C@H]1C[C@@H](NC=O)c2cc(ccc2N1C(C)=O)-c1ccc(CN2CCCCC2)cc1 |r| Show InChI InChI=1S/C25H31N3O2/c1-18-14-24(26-17-29)23-15-22(10-11-25(23)28(18)19(2)30)21-8-6-20(7-9-21)16-27-12-4-3-5-13-27/h6-11,15,17-18,24H,3-5,12-14,16H2,1-2H3,(H,26,29)/t18-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD4 (1 to 477 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50028127 (CHEMBL3353993) Show SMILES C[C@H]1C[C@@H](NC=O)c2cc(ccc2N1C(C)=O)-c1ccc(CN2CCCCC2)cc1 |r| Show InChI InChI=1S/C25H31N3O2/c1-18-14-24(26-17-29)23-15-22(10-11-25(23)28(18)19(2)30)21-8-6-20(7-9-21)16-27-12-4-3-5-13-27/h6-11,15,17-18,24H,3-5,12-14,16H2,1-2H3,(H,26,29)/t18-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD3 (1 to 475 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair